HGA Series Automatic Medicine Bottle Blow Molding Machine for Pharmaceutical & Healthcare Packaging
2–6 cavities · Up to 7,200 BPH · 500 ml – 1,500 ml container range · PET medicine bottle manufacturing · CE & ISO certified
Pharmaceutical Medicine Bottle Blow Molding Machine — Product Overview & Industry Fit
Pharmaceutical packaging sits in a different category from food or beverage production. The containers need to meet stricter dimensional tolerances — a pill bottle that doesn’t seat its cap correctly fails at the filling line, not after it leaves the factory. The HGA medicine bottle series was developed specifically for this reality: 9 models, from the compact 2-cavity AS-2C114.3 to the 6-cavity ES-6C76, each calibrated for the tight-tolerance requirements of pharmaceutical and healthcare bottle production.
Output ranges from 2,000 BPH on smaller 2-cavity models up to 7,200 BPH on the 6-cavity ES-6C76 — fast enough for high-speed medicine bottle blow molding machine requirements at mid-to-large pharmaceutical factories, but with the per-cavity precision that medical-grade containers demand.
Typical customers include pharmaceutical bottle manufacturers supplying API, OTC, and nutraceutical brands; hospital supply chain producers; veterinary medicine packagers; and contract packaging operations running multiple bottle formats on a single line. The PET medicine bottle manufacturing machine format in this series supports both standard round bottles and flat oval formats, with neck diameters from 18 mm (eye-drop scale) up to 130 mm (supplement jar format).
Why Choose Our Pharmaceutical Bottle Blow Molding Machine Over Generic PET Equipment
Pharmaceutical lines don’t get a second chance on tolerances. Here’s what specifically differentiates the HGA medicine bottle series:
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Neck Finish Precision
Neck diameter control is held to ±0.15 mm across the run. For child-resistant caps and snap-on dispensing closures, this is the difference between a passing and failing seating torque test.
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High-Speed Output with Stability
The ES-6C76 produces 7,200 BPH on 700 ml containers without sacrificing wall thickness uniformity. Servo-driven clamping maintains consistent mold closure force across every cycle — critical for maintaining reject rates below 0.3%.
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Zone-Controlled IR Heating
Independent control across multiple lamp groups means the shoulder, body, and base zones can be set independently. For pharmaceutical PET preforms with narrow IV ranges, this prevents over-stretch at the base — which causes stress whitening and reduces UV-barrier integrity.
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Fast Format Changeover
Pharmaceutical lines frequently switch between bottle SKUs. Common mold-mounting pitch across the AS and ES sub-series means a trained two-person team can swap mold sets in under 90 minutes and recall a saved PLC recipe for the new format without re-tuning.
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Cleanroom-Compatible Design
Lubrication points are isolated from the air circuit and blow zone. No mineral oil or grease enters the bottle interior during production — a non-negotiable requirement for pharmaceutical GMP environments. Clean-room enclosure options are available on request.
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Named-Brand Components
FESTO pneumatics, Siemens or equivalent PLC, TSUBAKI chain in the heating zone. Every critical component is from a brand with a global parts network — your maintenance team can source replacements locally without waiting for sea freight.
Medicine Bottle Types and Materials Supported by the HGA Pharmaceutical Bottle Making Machine
💊 Solid Dosage Bottles
Round tablet & capsule bottles, 500–1,500 ml, neck 68–130 mm. Designed for automatic filling lines with orientable neck-finish for child-resistant or push-and-turn closures.
💧 Liquid Medicine Bottles
Syrup, suspension, and oral solution containers, 100–1,000 ml. Narrow neck diameters down to 18 mm (ES-3C76) accommodate dropper and dosing-cup closures.
🧴 Nutraceutical & Supplement Jars
Wide-mouth vitamin, protein, and health supplement containers. Wide neck formats up to 130 mm on the AS-2C114.3 and ES-2C114.3 models, height up to 260 mm.
🐾 Veterinary & Agro-Pharma
Veterinary oral and topical medicine packaging. The 4-cavity and 6-cavity models allow cost-effective high-volume runs for animal health product lines where per-unit packaging cost is tightly controlled.
Materials supported:
- PET (Polyethylene Terephthalate) — Primary material for transparent pharmaceutical bottles. Excellent clarity for visual inspection, low gas permeability for moisture-sensitive products, and FDA/EU food-contact compliant grades are standard.
- PP (Polypropylene) — For containers requiring autoclave sterilization or higher chemical resistance. Supported on specific models; confirm at order stage as screw geometry differs from PET.
- rPET (Recycled PET) — Usable on all models with heating zone adjustment of ±8–12% across lamp groups to compensate for wider IV variance in recycled material grades.
Technical Specifications of the HGA Pharmaceutical Bottle Making Machine — All 9 Models
Each model spec is broken out individually for direct comparison. Scroll horizontally on mobile.
HGA.AS-2C114.3 — 2-Cavity Wide-Neck Supplement Jar Machine (1,000 ml)
Best for: Wide-mouth vitamin & supplement jars, 500–1,000 ml. Neck dia. up to 88 mm. Output: 2,000 BPH.
| Parameter | Unit | Value |
|---|
| Cavities | — | 2 |
| Max Container Volume | ml | 1,000 |
| Output | BPH | 2,000 |
| Clamping Stroke | mm | 122 |
| Mold-Open / Close Distance | mm | 302 / 180 |
| Stretching Stroke | mm | 400 |
| Bottle Pitch Distance | mm | 114.3 |
| Preform Holders | — | 48 |
| Max Neck Diameter | mm | 88 |
| Max Container Diameter | mm | 94 |
| Max Container Height | mm | 260 |
| Max / Normal Heating Power | kW | 45 / 20 |
| HP Air Consumption | ltr/min @ 35 kg/cm² | 1,600 |
| Cooling Water Flow | ltr/min | 30 |
| Machine Size (L×W×H) | mm | 2,660×1,660×2,150 |
| Machine Weight | kg | 2,600 |
HGA.AS-4C76.2 — 4-Cavity High-Speed Medicine Bottle Machine (500 ml)
Best for: Standard 500 ml oral solid dosage bottles. 4 cavities at 4,000 BPH — the entry point for high-speed medicine bottle blow molding machine performance.
| Parameter | Unit | Value |
|---|
| Cavities | — | 4 |
| Max Container Volume | ml | 500 |
| Output | BPH | 4,000 |
| Clamping Stroke | mm | 100 |
| Mold-Open / Close Distance | mm | 280 / 180 |
| Stretching Stroke | mm | 350 |
| Bottle Pitch Distance | mm | 76.2 |
| Preform Holders | — | 96 |
| Max Neck Diameter | mm | 48 |
| Max Container Diameter | mm | 65 |
| Max Container Height | mm | 250 |
| Max / Normal Heating Power | kW | 33 / 17 |
| HP Air Consumption | ltr/min @ 35 kg/cm² | 4,000 |
| Cooling Water Flow | ltr/min | 40 |
| Machine Size (L×W×H) | mm | 3,370×1,850×2,100 |
| Machine Weight | kg | 4,000 |
HGA.ES-2C100 — 2-Cavity Standard Medicine Bottle Machine (500 ml)
Best for: General-purpose 500 ml pharmaceutical bottles. Compact footprint at 2,900×1,525×1,930 mm. Output: 2,400 BPH.
| Parameter | Unit | Value |
|---|
| Cavities | — | 2 |
| Max Container Volume | ml | 500 |
| Output | BPH | 2,400 |
| Clamping Stroke | mm | 110 |
| Mold-Open / Close Distance | mm | 280 / 170 |
| Stretching Stroke | mm | 350 |
| Bottle Pitch Distance | mm | 100 |
| Preform Holders | — | 60 |
| Max Neck Diameter | mm | 68 |
| Max Container Diameter | mm | 80 |
| Max Container Height | mm | 200 |
| Max / Normal Heating Power | kW | 34 / 8–12 |
| HP Air Consumption | ltr/min @ 26–35 kg/cm² | 1,000–1,400 |
| Cooling Water Flow | ltr/min | 30 |
| Machine Size (L×W×H) | mm | 2,900×1,525×1,930 |
| Machine Weight | kg | 2,000 |
HGA.ES-2C114.3 — 2-Cavity Wide-Neck Pharmaceutical Jar Machine (1,000 ml)
Best for: 1 L supplement jars, wide-neck dispensing bottles. Neck up to 88 mm, body dia. up to 94 mm. Output: 2,000 BPH.
| Parameter | Unit | Value |
|---|
| Cavities | — | 2 |
| Max Container Volume | ml | 1,000 |
| Output | BPH | 2,000 |
| Clamping Stroke | mm | 132 |
| Mold-Open / Close Distance | mm | 312 / 180 |
| Stretching Stroke | mm | 400 |
| Bottle Pitch Distance | mm | 114.3 |
| Preform Holders | — | 60 |
| Max Neck Diameter | mm | 88 |
| Max Container Diameter | mm | 94 |
| Max Container Height | mm | 260 |
| Max / Normal Heating Power | kW | 50 / 16 |
| HP Air Consumption | ltr/min @ 35 kg/cm² | 1,000 |
| Cooling Water Flow | ltr/min | 30 |
| Machine Size (L×W×H) | mm | 3,220×1,660×2,010 |
| Machine Weight | kg | 3,000 |
HGA.ES-2C130 — 2-Cavity Large-Body Pharmaceutical Bottle Machine (1,500 ml)
Best for: Large supplement bottles and syrup containers up to 1,500 ml. Neck up to 98 mm, body dia. up to 110 mm. Output: 1,800 BPH.
| Parameter | Unit | Value |
|---|
| Cavities | — | 2 |
| Max Container Volume | ml | 1,500 |
| Output | BPH | 1,800 |
| Clamping Stroke | mm | 160 |
| Mold-Open / Close Distance | mm | 360 / 200 |
| Stretching Stroke | mm | 350 |
| Bottle Pitch Distance | mm | 130 |
| Preform Holders | — | 60 |
| Max Neck Diameter | mm | 98 |
| Max Container Diameter | mm | 110 |
| Max Container Height | mm | 250 |
| Max / Normal Heating Power | kW | 42.5 / 8–13 |
| HP Air Consumption | ltr/min @ 26–35 kg/cm² | 1,000–1,500 |
| Cooling Water Flow | ltr/min | 30 |
| Machine Size (L×W×H) | mm | 3,600×1,800×1,980 |
| Machine Weight | kg | 3,000 |
HGA.ES-3C76 — 3-Cavity Narrow-Neck Liquid Medicine Bottle Machine (700 ml)
Best for: Syrup, oral solution, and eye-drop format bottles. Narrow neck (18–38 mm range), 3 cavities at 3,000 BPH. Smallest footprint in the 3-cavity range.
| Parameter | Unit | Value |
|---|
| Cavities | — | 3 |
| Max Container Volume | ml | 700 |
| Output | BPH | 3,000 |
| Clamping Stroke | mm | 100 |
| Mold-Open / Close Distance | mm | 300 / 200 |
| Stretching Stroke | mm | 240 |
| Bottle Pitch Distance | mm | 76 |
| Preform Holders | — | 72 |
| Max Neck Diameter | mm | 18–38 |
| Max Container Diameter | mm | 68 |
| Max Container Height | mm | 240 |
| Max / Normal Heating Power | kW | 40 / 18 |
| HP Air Consumption | ltr/min @ 35 kg/cm² | 2,400 |
| Cooling Water Flow | ltr/min | 30 |
| Machine Size (L×W×H) | mm | 2,850×1,850×2,180 |
| Machine Weight | kg | 3,500 |
HGA.ES-4C76 — 4-Cavity High-Speed Pharmaceutical Bottle Machine (700 ml)
Best for: Standard 500–700 ml tablet & capsule bottles at scale. 4 cavities, 4,800 BPH — suited to medicine bottle blow molding machine for pharmaceutical factory lines running 2+ shifts.
| Parameter | Unit | Value |
|---|
| Cavities | — | 4 |
| Max Container Volume | ml | 700 |
| Output | BPH | 4,800 |
| Clamping Stroke | mm | 100 |
| Mold-Open / Close Distance | mm | 300 / 200 |
| Stretching Stroke | mm | 350 |
| Bottle Pitch Distance | mm | 76 |
| Preform Holders | — | 96 |
| Max Neck Diameter | mm | 48 |
| Max Container Diameter | mm | 68 |
| Max Container Height | mm | 240 |
| Max / Normal Heating Power | kW | 40 / 18 |
| HP Air Consumption | ltr/min @ 35 kg/cm² | 3,900 |
| Cooling Water Flow | ltr/min | 30 |
| Machine Size (L×W×H) | mm | 3,290×1,850×2,260 |
| Machine Weight | kg | 3,500 |
HGA.ES-4C100 — 4-Cavity Mid-Volume Pharmaceutical Bottle Machine (800 ml)
Best for: 800 ml oral solid and nutritional supplement bottles. Wider neck up to 68 mm. Output: 4,600 BPH. Higher compressor demand (4,000 ltr/min) suits integrated plant-air systems.
| Parameter | Unit | Value |
|---|
| Cavities | — | 4 |
| Max Container Volume | ml | 800 |
| Output | BPH | 4,600 |
| Clamping Stroke | mm | 128 |
| Mold-Open / Close Distance | mm | 328 / 200 |
| Stretching Stroke | mm | 350 |
| Bottle Pitch Distance | mm | 100 |
| Preform Holders | — | 92 |
| Max Neck Diameter | mm | 68 |
| Max Container Diameter | mm | 80 |
| Max Container Height | mm | 250 |
| Max / Normal Heating Power | kW | 62.5 / 21 |
| HP Air Consumption | ltr/min @ 35 kg/cm² | 4,000 |
| Cooling Water Flow | ltr/min | 30 |
| Machine Size (L×W×H) | mm | 4,170×1,930×2,340 |
| Machine Weight | kg | 4,000 |
HGA.ES-6C76 — 6-Cavity Flagship High-Speed Medicine Bottle Blow Molding Machine (700 ml)
Best for: Maximum-output pharmaceutical bottle lines — 7,200 BPH on 700 ml containers. The highest-speed model in this series. Requires 5,800 ltr/min HP air supply; plan for dedicated high-pressure compressor.
| Parameter | Unit | Value |
|---|
| Cavities | — | 6 |
| Max Container Volume | ml | 700 |
| Output | BPH | 7,200 |
| Clamping Stroke | mm | 100 |
| Mold-Open / Close Distance | mm | 300 / 200 |
| Stretching Stroke | mm | 350 |
| Bottle Pitch Distance | mm | 76 |
| Preform Holders | — | 130 |
| Max Neck Diameter | mm | 38 |
| Max Container Diameter | mm | 68 |
| Max Container Height | mm | 240 |
| Max / Normal Heating Power | kW | 62.5 / 26 |
| HP Air Consumption | ltr/min @ 35 kg/cm² | 5,800 |
| Cooling Water Flow | ltr/min | 40 |
| Machine Size (L×W×H) | mm | 4,690×2,000×2,000 |
| Machine Weight | kg | 5,500 |
Quick Model Selection Guide — Which Medicine Bottle Blow Molding Machine Fits Your Output Target?
| Model | Cavities | Volume | Output (BPH) | Best Use Case |
|---|
| AS-2C114.3 | 2 | 1,000 ml | 2,000 | Wide-neck supplement jars |
| AS-4C76.2 | 4 | 500 ml | 4,000 | Standard OTC tablet bottles |
| ES-2C100 | 2 | 500 ml | 2,400 | General pharma, compact lines |
| ES-2C114.3 | 2 | 1,000 ml | 2,000 | Wide-mouth pharma jars |
| ES-2C130 | 2 | 1,500 ml | 1,800 | Large syrup / supplement bottles |
| ES-3C76 | 3 | 700 ml | 3,000 | Narrow-neck liquid medicine |
| ES-4C76 | 4 | 700 ml | 4,800 | High-volume pharma factory lines |
| ES-4C100 | 4 | 800 ml | 4,600 | Mid-volume solid dosage bottles |
| ES-6C76 | 6 | 700 ml | 7,200 | Flagship — highest output in series |
Frequently Asked Questions — Pharmaceutical Medicine Bottle Blow Molding Machine
Q1: Does the HGA medicine bottle machine meet GMP requirements for pharmaceutical packaging?
The machine’s blow zone and air circuit are designed with no-contact lubrication isolation, preventing contamination of bottle interiors. Stainless-steel contact surfaces are standard. Clean-room enclosure and HEPA air-feed options are available. Buyers are responsible for site-level GMP qualification; we provide full IQ/OQ documentation packages on request.
Q2: Can one machine run both narrow-neck (18 mm) liquid medicine bottles and wide-neck (88 mm) supplement jars?
Not without a different machine frame, because the bottle pitch distance differs between the 76 mm (narrow neck) and 114.3 mm (wide neck) sub-series. For mixed production, two models are needed — or a mold changeover within the same pitch family. The ES-3C76 and ES-6C76 cover the narrow-neck range; AS/ES-xC114.3 covers wide necks.
Q3: What air compressor is required for the 6-cavity ES-6C76 high-speed medicine bottle machine?
The ES-6C76 needs 5,800 ltr/min at 35 kg/cm² for high-pressure blowing, plus 900 ltr/min at 7 kg/cm² low-pressure. Plan for a dedicated high-pressure compressor rated at least 6,400 ltr/min (10–15% buffer). Low-pressure can share a plant-air header if total demand allows.
Q4: Is the PET medicine bottle manufacturing machine compatible with recycled PET (rPET) preforms?
Yes. rPET has wider IV variance than virgin material (typically ±0.05 dl/g vs ±0.02 dl/g). The zone-controlled IR heating compensates by allowing ±8–12% lamp power adjustment per zone. Run a 2-hour trial batch when switching grades and adjust shoulder/base zones first. FDA-approved rPET grades are needed for primary pharmaceutical packaging.
Q5: How long is the lead time from order to commissioned production for a pharmaceutical bottle blow molding machine?
Standard lead time is 35–50 days from order confirmation to ex-factory. Add 10–20 days for sea freight depending on destination. On-site commissioning by our engineers is available — typically 3–5 days on-site. A full 8-hour factory acceptance test is run before shipment, with signed bottle-weight and dimension reports provided.
Request a Customized Pharmaceutical Bottle Production Solution
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